Run Boston.
Choose your charity.

Helping cancer patients and their families navigate the financial and emotional challenges as a result of a cancer diagnosis.

One Mission makes life brighter for children fighting cancer and their families, through programs and services that bring joy, comfort, and practical support during treatment. Every mile helps a child feel like a kid, not simply a patient.

DetecTogether empowers people to recognize important changes in their health, speak up, and take action so cancer can be detected as early as possible. Its lifesaving 3 Steps Detect education gives people a simple, practical framework for communicating with healthcare providers and advocating for answers. Every mile helps more people recognize warning signs early, when treatment is often most effective.

The Shawn Thornton Foundation supports the fight against cancer and Parkinson’s disease while assisting individuals and families affected by these illnesses. It raises funds for research, patient care, treatment programs, and organizations providing hope during incredibly difficult times. Every runner helps move this fight forward and honors the courage of patients, caregivers, and families.

The ALS Therapy Development Institute is relentlessly focused on discovering and developing effective treatments for ALS. As a nonprofit biotechnology organization, ALS TDI operates its own laboratory and advances promising science with urgency on behalf of people living with this devastating disease. Every dollar raised fuels research and brings the ALS community closer to treatments, and ultimately a cure.

Providing comfort, support and hope to cancer patients and their families

Journey Forward helps people living with spinal-cord injuries work toward greater strength, mobility, independence, and quality of life. Its intensive exercise-based programs provide ongoing support beyond traditional rehabilitation, creating opportunities for participants to continue pursuing progress. Every mile supports a community built on determination, possibility, and the refusal to give up.

The Brain Aneurysm Foundation is dedicated to increasing awareness, advancing early detection, supporting patients and families, and funding critical research. It gives people the information to recognize warning signs while helping scientists improve the diagnosis, treatment, and prevention of brain aneurysms. Every runner brings greater visibility and hope to a condition that is too often silent until it becomes life-threatening.

The Massachusetts Down Syndrome Congress works to ensure that people with Down syndrome are valued, included, and given every opportunity to pursue fulfilling lives. Through advocacy, education, resources, and community-building, MDSC supports individuals with Down syndrome and their families at every stage of life. Every mile helps advance a future defined by opportunity, dignity, and belonging.

The David Ortiz Children’s Fund helps children in New England and the Dominican Republic gain access to lifesaving cardiac care and other essential pediatric health services. Working with trusted medical partners, the fund helps children receive treatment regardless of their families’ ability to pay. Every runner gives a child a stronger heart and a greater chance to grow, thrive, and dream.

The Bionic Project aims to create a more inclusive world for everybody regardless of physical ability. We dismantle disability bias, build empathy, and foster connection through education, story, and sport.

Empowering underserved student-athletes in Boston to reach their potential in the classroom, in competition, and in life through education, training, and mentorship.

The New England Patriots Foundation strengthens communities throughout New England by supporting programs focused on education, health, family well-being, diversity, and youth development. It uses the platform of the Patriots to amplify community organizations and celebrate people creating positive change. Every runner helps extend those resources and opportunities to neighbors across the region.

Roxbury Community College provides an accessible, affordable, and transformative education to students from Greater Boston’s diverse communities. Through degree programs, workforce training, and community partnerships, RCC prepares students for further education, meaningful careers, and civic leadership. Every runner helps open doors for students working to build stronger futures for themselves and their families.

Supporting South Boston families since 1901 with Early Education & Care, Youth Programs, Family Engagement and 'Club 55' Programs for Older Adults.

Boston SCORES helps young people discover their voices, strengthen their bodies, and become leaders in their communities. Its free after-school programs combine soccer, poetry, creative expression, and community service for students across Boston. By supporting Boston SCORES, runners help children build confidence, connection, and a lasting belief in their own potential.

Honoring Boston Marathon bombing victim Lingzi Lu by providing educational, social, and athletic opportunities and honoring culture through community and kindness.

Doc Wayne harnesses the healing power of sport to improve the mental health and emotional well-being of young people. Its innovative programs combine movement, teamwork, and clinical therapy to make mental-health support more approachable, engaging, and accessible. Every mile helps create spaces where young people can feel safe, build resilience, and rediscover their strength.

The Light Foundation helps young people develop the values and skills needed to become confident, responsible leaders. Through outdoor experiences, mentorship, education, and character-development programs, participants learn the importance of hard work, accountability, service, and respect. Every runner helps young people discover their strengths and build the courage to lead with purpose.

The Pedro Martinez Foundation creates brighter futures for children and families facing poverty in the Dominican Republic and the United States. Its programs address education, healthcare, nutrition, sports, personal development, and family stability so young people can break cycles of disadvantage. Every mile helps children gain the support and opportunity to realize their God-given potential.

St. Francis House helps adults experiencing homelessness and poverty rebuild their lives with dignity, stability, and hope. As New England’s largest daytime shelter, it offers meals, clothing, behavioral healthcare, recovery support, job preparation, and pathways to permanent housing. Its compassionate, comprehensive care meets people where they are and helps them take meaningful steps toward a better future.

One World Strong Foundation connects survivors of terrorism, mass violence, and traumatic events with a global community of people who understand their experiences. Through peer support, shared resources, and meaningful relationships, the foundation helps survivors navigate healing and rediscover hope. Its work transforms isolation into connection and reminds survivors that they are never alone.

Camp Harbor View partners with Boston youth and their families to build pathways toward healthy, successful futures. Beginning in middle school and continuing into early adulthood, its year-round programs offer community, leadership development, academic guidance, career preparation, and family support. Every runner helps young people recognize their potential and gain the relationships and resources to achieve it.

The Matt Brown Foundation stands beside individuals and families confronting paralysis and the enormous physical, emotional, and financial challenges that can follow. It provides quality-of-life grants for accessible vehicles, adaptive equipment, home modifications, and other essential needs that can restore independence. Rooted in resilience and the belief that no one should face paralysis alone, the foundation helps people keep moving forever forward.

Blue Square Alliance Against Hate educates and inspires people to recognize and stand up against antisemitism and hate in all its forms. Through research, national awareness campaigns, partnerships, and community action, it gives people the knowledge and tools to speak out. Every runner helps carry a simple but urgent message: hate cannot go unanswered.

Using the power of basketball to connect youth and women to healthier futures in both Boston and Rwanda.

The Urban League of Eastern Massachusetts empowers African American adults and other underserved communities to achieve economic independence and social equality. Through job training, career advancement, digital education, financial coaching, and advocacy, it helps people overcome systemic barriers and build lasting stability. Every mile supports a more equitable region where talent and ambition have room to flourish.

Providing free lodging for military families (active, guard, veteran, or retired) while a loved one is receiving care at any of Boston's world-renowned medical centers.

Military Friends Foundation supports Massachusetts service members, veterans, and military families facing financial hardship and the lasting effects of military service. Its programs provide emergency assistance, family support, community connection, and meaningful remembrance of the fallen. Every mile is an opportunity to stand behind the people who serve, and the families who sacrifice alongside them.

The Esplanade Association works to care for and enhance Boston’s iconic Charles River Esplanade so that it remains beautiful, welcoming, and accessible to everyone. In partnership with the state, the organization improves the park’s landscapes, facilities, programs, and gathering spaces. Its work protects a treasured place where people can run, play, connect, and experience the restorative power of nature.

Protecting, restoring, and enhancing the Charles River and its watershed through science, advocacy, and the law since 1965.

The Hoyt Foundation champions the inclusion of people with disabilities in sports and every aspect of community life. Inspired by the extraordinary bond between Dick and Rick Hoyt, it helps athletes with disabilities participate, compete, and experience the freedom and connection of movement. Every mile carries forward Team Hoyt’s enduring message: yes, you can.

The MEB Foundation inspires young people and families to lead healthy, active, and engaged lives. Founded by champion runner Meb Keflezighi, it supports programs that make fitness, education, and healthy living more accessible to children from all backgrounds. Every mile helps young people discover the confidence, discipline, and joy that come from moving forward.

The Dave McGillivray Finish Strong Foundation inspires young people to build healthy, confident, and compassionate lives through running, reading, and acts of kindness. Its programs demonstrate that physical activity, education, and service can give children the self-belief to pursue ambitious goals. Every runner helps the next generation dream big, persevere, and finish strong.

Advancing safety awareness, violence prevention, and the empowerment of women — especially in the running community — in memory of Vanessa Marcotte.

Marathon Kids motivates children to become more active, one mile and one achievable goal at a time. Its inclusive running and walking programs help young people develop healthy habits while building confidence, perseverance, and a lifelong appreciation for movement. Every runner helps another child discover that they are capable of going farther than they imagined.